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There are numerous long-term consequences of untreated sleep apnea, including the following issues:

Cardiovascular:

  • high blood pressure (hypertension)
  • heart attacks (myocardial infarction or MI)
  • angina (chronic chest pain)
  • atrial fibrillation ("a fib")
  • cor pulmonale (right heart failure)
  • stroke (cerebrovascular event or CVA)
  • TIA ("mini-stroke")
  • congestive heart failure (CHF)
  • increased risk of sudden death

Neurological (Brain):

  • migraine
  • cluster headaches
  • chronic daily headache
  • increased seizure frequency for those with epilepsy
  • pseudotumor cerebri (idiopathic intracranial hypertension - "IIH")
  • memory disorders

Pulmonary:

  • pulmonary hypertension
  • asthma

Metabolic:

  • Type 2 diabetes
  • insulin resistance
  • hypothyroidism
  • metabolic syndrome
  • high cholesterol (dyslipidemia or hyperlipidemia)
  • nonalcoholic fatty liver disease 

Urological:

  • erectile dysfunction (ED)
  • nocturia (excessive nighttime urination)

Ophthalmologic (Eye):

  • floppy eyelid syndrome
  • glaucoma
  • conjunctivitis

Psychiatric/Psychological:

  • depression
  • mood disturbance
  • ADHD
  • insomnia

Pregnancy-related:

  • preeclampsia

Surgical/Procedural:

  • increased risk of perioperative complications

Other Sleep Disorders:

  • confusional arousals
  • sleepwalking
  • sleep terrors
  • pseudo-REM sleep behavior disorder (RBD)
  • sleep related eating disorder
  • OSA-induced nocturnal seizures
  • cerebral anoxic attacks with motor activity